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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LETM1
All Species:
19.7
Human Site:
S580
Identified Species:
36.11
UniProt:
O95202
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95202
NP_036450.1
739
83354
S580
K
E
D
V
Q
D
Y
S
E
D
L
Q
E
I
K
Chimpanzee
Pan troglodytes
XP_001171298
444
50543
E321
Q
L
R
Q
Q
L
T
E
W
Q
D
L
H
L
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545925
741
83362
S581
K
E
D
V
Q
D
Y
S
E
D
L
Q
E
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2I0
738
82970
S579
K
E
D
V
Q
D
Y
S
E
D
L
Q
E
I
K
Rat
Rattus norvegicus
Q5XIN6
739
83041
S579
K
E
D
V
Q
D
Y
S
E
D
L
Q
E
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516696
577
64046
S454
D
H
K
D
A
E
T
S
P
G
A
P
L
G
P
Chicken
Gallus gallus
Q5ZK33
752
85831
Y591
L
K
G
D
I
Q
E
Y
N
E
D
L
Q
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LY46
757
86828
S595
K
D
D
V
Q
E
Y
S
E
D
L
E
E
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91927
1013
113562
D594
E
L
K
E
E
L
A
D
Y
K
E
D
V
E
E
Honey Bee
Apis mellifera
XP_624231
764
87758
A576
Q
T
N
T
S
K
T
A
E
E
L
V
K
I
D
Nematode Worm
Caenorhab. elegans
NP_506381
784
88704
E530
H
D
I
L
G
L
R
E
K
V
L
E
H
K
E
Sea Urchin
Strong. purpuratus
XP_781116
544
61879
A421
E
L
Q
S
A
C
Q
A
R
G
M
R
A
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08179
573
64987
E450
E
T
A
I
P
K
E
E
A
T
A
K
E
S
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.2
N.A.
85.8
N.A.
83.9
83.6
N.A.
55
73.5
N.A.
63.5
N.A.
30.3
34.1
35.2
20.4
Protein Similarity:
100
46.9
N.A.
91.3
N.A.
89.1
89
N.A.
62.2
83.9
N.A.
78.7
N.A.
46
56.6
56.6
38.5
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
6.6
0
N.A.
80
N.A.
0
20
6.6
0
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
13.3
20
N.A.
100
N.A.
20
53.3
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
16
0
8
16
8
0
16
0
8
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
16
39
16
0
31
0
8
0
39
16
8
0
0
8
% D
% Glu:
24
31
0
8
8
16
16
24
47
16
8
16
47
16
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
0
16
0
0
0
8
8
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% H
% Ile:
0
0
8
8
8
0
0
0
0
0
0
0
0
47
8
% I
% Lys:
39
8
16
0
0
16
0
0
8
8
0
8
8
8
47
% K
% Leu:
8
24
0
8
0
24
0
0
0
0
54
16
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
8
% P
% Gln:
16
0
8
8
47
8
8
0
0
8
0
31
8
0
0
% Q
% Arg:
0
0
8
0
0
0
8
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
47
0
0
0
0
0
8
0
% S
% Thr:
0
16
0
8
0
0
24
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
39
0
0
0
0
0
8
0
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
39
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _